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What Is Sickle Cell Anemia? Symptoms, Causes, and Treatment Options

Sickle Cell Anemia is an inherited blood disorder that affects millions of people worldwide, particularly in nations such as Sub-Saharan Africa, India, and the Mediterranean. It causes red blood cells to alter their shape and become crescent or sickle-shaped cells, which reduces their oxygen-carrying capacity and leads to various health complications. Red blood cells in healthy individuals are usually elastic and round, moving freely through the blood vessels. In Sickle Cell Anemia, red blood cells are stiff and sickle-shaped. Because of their bizarre shape, they block small blood vessels, which can cause pain and damage to organs like the heart, lungs, and kidneys. Sickle Cell Anemia is inherited, therefore, a child must receive the sickle cell gene from both parents to be ill. Persons who have only one sickle cell gene are carriers (sickle cell trait), but they will not necessarily get sick. As a leading medical tourism company, My Care India strives to provide accessible, world-class healthcare to those seeking treatment for Sickle Cell Anemia.

Symptoms of Sickle Cell Anemia

The symptoms of Sickle Cell Anemia can vary with each person, but the most common are:
1. Pain Crises: Severe, sudden pain, typically in bones, chest, or abdomen, due to blood vessel blockage.
2. Fatigue: Reduced oxygen delivery by sickle-shaped cells induces weakness and fatigue.

What Is Sickle Cell Anemia? Symptoms, Causes, and Treatment

3. Paleness or Jaundice: Breakdown of red blood cells can lead to pale colour or yellow discolouration of the skin and eyes.
4. Swelling in Hands and Feet: Decreased circulation causes painful swelling in hands and feet.
5. Delayed Growth: Children with Sickle Cell Anemia may experience slower growth and development.

Causes of Sickle Cell Anemia

Sickle Cell Anemia occurs due to a mutation of the gene that encodes for haemoglobin, which is the oxygen-carrying protein in red blood cells. When both parents are carriers of the sickle cell gene, there is a 25% chance that the child will acquire the disease. Those who are carriers of a single copy of the gene do not typically develop the disease.

Treatment for Sickle Cell Anemia

Sickle Cell Anemia is a lifelong condition, but advancements in treatments have significantly improved the quality of life for individuals living with the disease.

Here are the main treatment options available for Sickle Cell Anemia:
1. Pain Management: Medications are used to alleviate pain occurring at the time of crisis, which ranges from mild to severe.
2. Hydroxyurea: The medication reduces the frequency of pain and, potentially, prevents complications by stimulating normal red cell production.
3. Blood Transfusions: Regular blood transfusions can potentially raise the count of good red blood cells and avoid complications like stroke.
4. Stem Cell or Bone Marrow Transplants: In some cases, a stem cell or bone marrow transplant can be a potential cure by replacing diseased bone marrow with healthy cells.
5. Gene Therapy: While still in experimental stages, gene therapy is promising to be a long-term cure by repairing the genetic defect that leads to the disease.

What Is Sickle Cell Anemia? Symptoms, Causes, and Treatment

Conclusion

For individuals seeking quality, affordable Sickle Cell Anemia treatment, India has some of the world's best medical facilities. My Care India partners with top hospitals and experienced doctors to provide comprehensive care, from pain relief to advanced procedures like stem cell transplants. If you or your loved one is having trouble with this disease, My Care India can help you find the best Sickle Cell Anemia treatment in India. Our staff offers personalized care and helps you gain access to the best medical treatments available, offering the best quality of life and health outcomes. Let us assist you in deciding on your treatment options and take the next step toward better health.

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